BRIVIACT® (brivaracetam) CV is a prescription medicine that can be used to treat partial-onset (focal) seizures in people 4 years of age and older. It is not known if BRIVIACT injection is safe for use in children. Children 4 years of age and older should only take BRIVIACT by mouth. BRIVIACT injection is only for use in people 16 years of age and older and may be given in the vein (intravenously) when BRIVIACT is not able to be taken by mouth. It is not known if BRIVIACT is safe and effective in children younger than 4 years of age.
BRIVIACT® (brivaracetam) CV oral formulations are prescription medicines that can be used to treat partial-onset (focal) seizures in people 4 years of age and older.

Taking BRIVIACT

How should I take BRIVIACT?

  • Take BRIVIACT exactly as your healthcare provider tells you. He or she will tell you how much BRIVIACT to take and when to take it
  • Take your prescribed dose on day one. BRIVIACT does not require titration — this means that you do not need to increase your dose over several weeks
  • For adults, the recommended starting dose is 50 mg twice daily (100 mg per day)

BRIVIACT® (brivaracetam) CV dosing chart

  • Your healthcare provider may change your dose if needed. For adults, he or she may lower the dose to 25 mg twice daily (50 mg per day) or increase your dose to 100 mg twice daily (200 mg per day)
  • The recommended dosing for patients aged 4 to less than 16 years of age is based on the patient's weight. Please talk to your healthcare provider for additional information and you can also click here for the Prescribing Information
  • Do not stop BRIVIACT or change your dose without talking to your healthcare provider
  • Take BRIVIACT with or without food
  • Swallow BRIVIACT tablets whole with a liquid. Do not chew or crush BRIVIACT tablets before swallowing
  • Do not take BRIVIACT if you are allergic to brivaracetam or any of the inactive ingredients in BRIVIACT
  • If your healthcare provider has prescribed BRIVIACT oral solution, be sure to ask your pharmacist for a medicine dropper or medicine cup to help you measure the correct amount of BRIVIACT oral solution. Do not use a household teaspoon. Ask your pharmacist for instructions on how to use the measuring device right away
  • If you take too much BRIVIACT, call your Poison Control Center at 1-800-222-1222 or go to the nearest emergency room right away.

I'm doing well. Can I stop taking BRIVIACT?

Taking your epilepsy medicine exactly as your doctor recommends is one of the most important things you can do to help manage your seizures. Do not stop taking your medicine if your seizures become less frequent or stop altogether. BRIVIACT is a daily treatment, so you must continue taking it until your doctor tells you to stop. If your doctor decides to stop your BRIVIACT treatment, he or she will give you instructions to slowly stop taking BRIVIACT.

Do not stop taking BRIVIACT without first talking to a healthcare provider. Stopping BRIVIACT suddenly can cause serious problems, including seizures that will not stop (status epilepticus).

Tips to help you remember your medicine

When you're taking many different medicines, keeping track of when to take them and how much to take can be challenging. Here are some strategies to help make keeping up with your medicines a little easier:

  • Use a pillbox
    Using a pillbox will help you remember to take your medicine and help prevent double doses.
  • Create a routine
    Get into the habit of taking your epilepsy medicine at the same times each day.
  • Keep it visible
    Leave your medicine in a place where it will be easy to spot.
  • Turn to technology
    Set up a digital medicine reminder on your phone, watch or computer.
  • Ask a loved one
    Ask your loved one for a gentle reminder to take your medicine.

IMPORTANT SAFETY INFORMATION

What is BRIVIACT?

BRIVIACT® (brivaracetam) CV is a prescription medicine used to treat partial-onset seizures in people 4 years of age and older.

  • It is not known if BRIVIACT injection is safe for use in children.
  • Children 4 years of age and older should only take BRIVIACT by mouth.
  • BRIVIACT injection is only for use in people 16 years of age and older and may be given in the vein (intravenously) when BRIVIACT is not able to be taken by mouth.

It is not known if BRIVIACT is safe and effective in children younger than 4 years of age.

What is the most important information I should know about BRIVIACT?

BRIVIACT is a federally controlled substance (CV) because it can be abused or lead to dependence. Keep BRIVIACT in a safe place to prevent misuse and abuse. Selling or giving away BRIVIACT may harm others and is against the law.

Like other antiepileptic drugs, BRIVIACT may cause suicidal thoughts or actions in a very small number of people, about 1 in 500 people taking it.

Call a healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you:

  • thoughts about suicide or dying
  • attempts to commit suicide
  • new or worse depression
  • new or worse anxiety
  • feeling agitated or restless
  • panic attacks
  • trouble sleeping (insomnia)
  • new or worse irritability
  • acting aggressive, feeling angry, or being violent
  • acting on dangerous impulses
  • an extreme increase in activity and talking (mania)
  • other unusual changes in behavior or mood

Do not stop BRIVIACT without first talking to a healthcare provider.

  • Stopping BRIVIACT suddenly can cause serious problems.
  • Stopping a seizure medicine suddenly can cause seizures that will not stop (status epilepticus).

Who should not take BRIVIACT?

Do not take BRIVIACT if you are allergic to brivaracetam or any of the inactive ingredients in BRIVIACT.

What should I tell my healthcare provider before starting BRIVIACT?

Before taking BRIVIACT, tell your healthcare provider about all of your medical conditions, including if you:

  • have or have had depression, mood problems, or suicidal thoughts or behavior
  • have liver problems
  • have abused or been dependent on prescription medicines, street drugs, or alcohol
  • have any other medical problems
  • are pregnant or plan to become pregnant. It is not known if BRIVIACT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if BRIVIACT passes into your breast milk.

What should I avoid while taking BRIVIACT?

Do not drive or operate heavy machinery until you know how BRIVIACT affects you. BRIVIACT may cause drowsiness, tiredness, dizziness, and problems with your balance and coordination.

What are the possible side effects of BRIVIACT?

BRIVIACT may cause serious side effects, including:

  • See “What is the most important information I should know about BRIVIACT?”
  • Nervous system problems. Drowsiness, tiredness, and dizziness are common with BRIVIACT, but can be severe. See “What should I avoid while taking BRIVIACT?” BRIVIACT can also cause problems with balance and coordination.
  • Mental (psychiatric) symptoms. BRIVIACT can cause mood and behavior changes such as aggression, agitation, anger, anxiety, apathy, mood swings, depression, hostility, and irritability. Irritability and anxiety are common with BRIVIACT, and can be severe. People who take BRIVIACT can also get psychotic symptoms such as hallucinations (seeing or hearing things that are really not there), delusions (false or strange thoughts or beliefs), and unusual behavior.

The most common side effects of BRIVIACT include:

  • sleepiness
  • dizziness
  • feeling tired
  • nausea and vomiting

Side effects of BRIVIACT in children 4 to less than 16 years of age are similar to those seen in adults.

These are not all the possible side effects of BRIVIACT. For more information, ask your healthcare provider or pharmacist. Tell your healthcare provider about any side effect that bothers you or that does not go away. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects to UCB, Inc. at UCBCares® (1-844-599-CARE [2273]).

Please see additional patient information in the Medication Guide. This information does not take the place of talking with your healthcare provider about your condition or your treatment. For more information, go to www.BRIVIACT.com or call 1-844-599-2273.